Despite that being the case, the 49ers are actually slight road favorites in this thrilling contest. On the other side, the Eagles have stayed hot all year, boasting a league-best 10-1 record. After a mid-season slump, the Niners have bounced back in a big way, entering this matchup on a three-game winning streak. (ET) slate is headlined by a rematch of last year’s NFC Championship, as the San Francisco 49ers travel to Philadelphia to take on the Eagles. That said, the Lions are solid road favorites as they look to bounce back. Dan Campbell’s squad barely pulled off the comeback against the Chicago Bears in Week 11, and they were outplayed all throughout last Thursday’s loss to the Green Bay Packers. Despite boasting an 8-3 record, it’s been a shaky few weeks for the Lions. The Detroit Lions travel to New Orleans to take on the Saints this Sunday. Dak Prescott and company are sizable favorites in Dallas. Week 13 of the 2023 NFL season kicks off with a Thursday Night Football matchup between the Seattle Seahawks and Dallas Cowboys! Seattle is looking to get back on track after dropping back-to-back contests, while the Cowboys are riding a three-game winning streak entering this matchup.